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We identified 18 sequence variants associated with NAFL and 4 with cirrhosis, and found rare, protective, predicted loss-of-function variants in MTARC1 and GPAM , underscoring them as potential drug targets

[] The three D-penicillamine functional groups (thiol, amino and carboxyl groups) are shown in Figure 6 and they are responsible for its distinctive chemical reactions among which is its metal-chelating ability

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In colitis models, LXR activation increases colonic crypt cell proliferation and colon length, indicating its pro-regenerative role in response to intestinal injury (148)